Hormonal factors that stimulate spermatogenesis

Hormonal factors that stimulate spermatogenesis :

1. LH secreted by anterior pituitary stimulates leydig cells to secrete testosterone.

2. Testosterone secreted by leydig cells is essential for growth and division of germinal cells in forming sperms.

3. FSH also secreted by anterior pituitary stimulates secretion of sertoli cells and without this stimulation spermatogenesis will not occur, in addition it promotes production of ABP.

4. Estrogen formed by sertoli cells essential for spermatogenesis, ABP is important for sperm maturation (capability of movement).

5. GH promotes early division of spermatogonia and its absence results in deficient or absence spermatogenesis (in dwarf).

6. Prolactin it may potentiate the stimulatory effect of LH on lydig cells and of testosterone on many of its target cells (in hyperprolactinemia causes infertility).