Mitochondria:
The mitochondria
also called the “power houses” of the
cell. Without them, cells would be unable to extract enough energy from the nutrients, and essentially all cellular
functions would cease. Mitochondria are present in all areas of each cell’s cytoplasm,
but the total number per cell
varies from less than a hundred up to several thousand,
depending on the amount of energy
required by the cell. Further, the mitochondria are concentrated in those
portions of the cell that are responsible for the major share of its energy metabolism. They are also variable
in size and
shape. it composed mainly of two lipid bilayer –protein membranes:
an outer membrane and an inner membrane. Many infoldings of
the inner membrane form shelves onto
which oxidative enzymes are attached; the
inner cavity of the mitochondrion is
filled with a matrix that contains large quantities of dissolved enzymes
that are necessary for extracting energy from nutrients.
These enzymes operate
in association with the oxidative enzymes on the shelves to cause oxidation of
the nutrients, thereby forming carbon dioxide
and water and at the same time releasing
energy. The liberated energy is used to synthesize a “high-energy” substance
called adenosine triphosphate (ATP).ATP is then transported out
of the mitochondrion, and it diffuses throughout the cell to release its own energy wherever it is
needed for
performing cellular function. Mitochondria
are self replicative, which means that one mitochondrion can form a second one,
a third one, and so on, whenever there is a need in the cell for increased
amounts of ATP. Indeed, the mitochondria contain DNA similar to that
found in the cell nucleus. The DNA of the mitochondrion plays a role in
controlling replication of the mitochondrion itself.
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