Vitamin K
Vitamin K deficiency leads to
delayed coagulation and bleeding. In obstructive jaundice, dietary vitamin K is
not absorbed
and it is essential to administer the vitamin in parenteral form
before surgery. Warfarin and related anticoagulants act by antagonising vitamin
K. Vitamin K is given routinely to newborn babies to prevent haemorrhagic
disease. Symptoms of excess have been reported only in infants, with synthetic
preparations linked to haemolysis and liver damage.
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